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Afirma Genomic Test | 2024 American Association of Clinical Endocrinology | Double TERT | Patient Case Study
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Afirma Genomic Test | 2023 American Thyroid Association Poster Presentation | Immunophenotyping
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Afirma Genomic Test | 2023 American Thyroid Association Poster Presentation | Isthmus
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Afirma Genomic Test | 2023 American Thyroid Association Poster Presentation | NIS
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AMP Data: Assessment of BRAF Fusions in 177,227 Thyroid Nodules by Exome-Enriched RNA-Seq Testing
November 2024
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ATA Data: Polyamine and Methionine Metabolism Gene Expression Analysis in Thyroid Tumors
November 2024
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ATA Data: Distinct Molecular Profiles of Thyroid Nodules in Patients Under 21 Years of Age
November 2024
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ATA Data: Clinical Performance of the Afirma Genomic Sequencing Classifier (GSC) in Pediatric Patients With Cytologically Indeterminate Thyroid Nodules
November 2024
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ENDO Data – Prostate-Specific Membrane Antigen (PSMA) Expression in Cytologically Indeterminate and Malignant Thyroid Nodules
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ENDO Data – Retrospective Analysis of mRNA Expression Based Signatures of Thyroid Tumor Invasion and Metastases
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AACE Data: Efficacy of Radiofrequency Ablation for Afirma Genomic Sequencing Classifier (GSC) Benign Indeterminate Thyroid Nodules
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AACE Data: First Report of Pre-Operative Detection of Two TERT Promoter Mutations Within a Papillary Thyroid Carcinoma
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JCEM Data: Analytical Validation of a Telomerase Reverse Transcriptase (TERT) Promoter Mutation Assay
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ATA Data: Sodium Iodide Symporter (NIS) Expression in Cytologically Indeterminate and Malignant Thyroid Nodules
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ATA Data: Molecular Assessment of Isthmus Thyroid Carcinomas
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ATA Data: Leveraging RNA Sequencing for Pre-Operative Immunophenotyping of BRAFV600E+ Thyroid Nodules
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ENDO Data: Cytologic and Molecular Assessment of Isthmus Thyroid Nodules
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AACE Data – Histopathology of Telomerase Reverse Transcriptase Promoter (TERT) Mutated Indeterminate Thyroid Nodules
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JCEM data – Real world performance of the Afirma Genomic Sequencing Classifier (GSC) – a meta analysis
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Thyroid – Preoperative identification of medullary thyroid carcinoma (MTC): Clinical validation of the Afirma MTC RNA-Sequencing classifier
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Cancer Cytopathology – The Afirma Xpression Atlas for Thyroid Nodules and Thyroid Cancer Metastases: Insights to Inform Clinical Decision-Making from a Fine-Needle Aspiration Sample
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ENDO Oral Data – Identification of Novel and Rare Receptor Tyrosine Kinase Fusions in Thyroid Fine Needle Aspirates
(ENDO 2020 canceled due to COVID-19)
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ENDO Data – Positive Predictive Value of TP53 Variants in Bethesda III/IV Thyroid Fine-Needle Aspirates
(ENDO 2020 canceled due to COVID-19)
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JCEM – Real World Comparison of Afirma GEC and GSC for the Assessment of Cytologically Indeterminate Thyroid Nodules (Cleveland Clinic)
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Cancer Cytopathology – Performance of the Afirma Genomic Sequencing Classifier Versus Gene Expression Classifier: An Institutional Experience (Fox Chase)
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Frontiers in Endocrinology – Afirma Xpression Atlas Clinical & Analytical Validation Study
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Thyroid Journal – Molecular Variants and Their Risks for Malignancy in Cytologically Indeterminate Thyroid Nodules
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ASCO Data – New Afirma Data Shows Potential to Guide Targeted Treatment for Medullary Thyroid Cancer
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Thyroid Journal – Independent Comparison of the Afirma Genomic Sequencing Classifier and Gene Expression Classifier for Cytologically Indeterminate Thyroid Nodules (B&W)
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Cancer Cytopathology – Extending expressed RNA genomics from surgical decision making for cytologically indeterminate thyroid nodules to targeting therapies for metastatic thyroid cancer
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BMC Systems Biology – Identification of Hürthle Cell Cancers: Solving a Clinical Challenge with Genomic Sequencing and a Trio of Machine Learning Algorithms
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ENDO Data – New Afirma Xpression Atlas Data Advances Genomic Understanding of Medullary Thyroid Cancer
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Endocrine Practice – Statistical Comparison of Afirma GSC and Afirma GEC Outcomes in a Community Endocrine Surgical Practice: Early Findings (Memorial Healthcare)
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ATA Data – Interview with Christian Nasr, MD: Performance of Afirma Genomic Sequencing Classifier: The Initial Cleveland Clinic Experience
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ATA Data – Interview with Erik Alexander, MD: Comparison of the Afirma Genomic Sequencing Classifier and Gene Expression Classifier for Cytologically Indeterminate Thyroid Nodules
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ATA Data – Interview with Jennifer A. Sipos, MD: Experience with the Genomic Sequencing Classifier in >100 Cytologically Indeterminate Thyroid Nodules
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Interview with R. Mack Harrell, MD: Afirma GSC: Early Endocrine Surgery Practice Performance 8/2017-2/2018
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Interview with Peter M. Sadow, MD, PhD: Detecting Expressed Variants and Fusions in RNASeq Data from Thyroid FNAs
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Interview with Christian Nasr, MD: Independent Academic Medical Center Afirma GSC Experience
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Interview with Joshua Babiarz, PhD: The Mutational Landscape of 774 Variants and 132 Fusions in 513 Genes Measured in Thyroid FNAs from a Multicenter Blinded Cohort
March 2018
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Interview with Michael Shanik, MD: Afirma Genomic Sequencing Classifier Experience Among the First 5478 Consecutive Samples
March 2018
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Interview with R. Mack Harrell, MD: Reduced Surgery through Afirma GEC: Impact to date and potential for the future
May 2017
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Interview with Brian Michael, MD: Six-year Clinical and Imaging Follow-up of an Office-based Gene Expression Classifier
May 2017
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Interview with Whitney Goldner, MD: Institutional Experience with Afirma GEC after Repeat Biopsy
April 2017
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Interview with Matthew J. Levine, MD, FACE: Five Year Experience with Afirma Gene Expression Classifier (GEC)
September 2016
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Interview with Jennifer A. Sipos, MD: Long-Term Follow-Up of Afirma GEC Benign Results
September 2016
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Interview with Ying Hu, MD, PhD: More Incidental Thyroid Malignancies Observed in the Lobes with a GEC Suspicious Nodule
September 2016
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UCLA Study Evaluates Whether Afirma GEC Has Refined the Indeterminate Cytology Category
May 2016
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New Multicenter Long-term Outcome Study Demonstrates Durable Afirma GEC Benign Results
March 2016
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New Long-Term Follow-Up Study Demonstrates that Afirma GEC Benign Nodules Behave Similarly to Nodules with Benign Cytology
January 2016
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Nine New Studies Demonstrate Utility and Long-Term Durability of Afirma GEC (Gene Expression Classifier)
November 2015
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Case Study: Genomic Analysis Identifies Medullary Thyroid Carcinoma
May 2015
